Collect. Transport.
Process. Store.

Our state-of-the-art process
ensures safety and security every
step of the way.

Our state-of-the-art process ensures safety and security every step of the way.

State-of-the-art insulated collection kit

Temperature is an important factor in maintaining the cells in transport and storage. StemCyte™ provides an insulated collection kit that can maintain the correct temperature of your valuable cord blood cells in the most challenging scenarios. Our kit was validated against ISTE standards.

Collection

After your baby is born and before the placenta is delivered, the umbilical cord is clamped and cut, the same as it would be for any normal delivery. The cord is rigorously cleaned to ensure a sterile collection, and then the cord blood is collected by your healthcare professional. All necessary materials for collecting and shipping are contained in the collection kit sent to the parents, so the hospital does not need to provide any materials.

The collection is done by inserting a sterile needle into the umbilical vein and allowing gravity to drain the blood into a collection bag. The collection bag is a closed system, which is preferred by transplant physicians because it minimizes the risk of bacterial and fungal contamination.

Transport

StemCyte™ uses insulated containers to keep your baby's cord blood cool throughout transport. These containers are tested and proven to maintain an optimum temperature during shipment under all climate conditions. This is vital to preserve the number and function of the collected cells, because heat or freezing during transport can damage the cells.

After collection, your baby's cord blood bag and all necessary paperwork are sealed and placed in the transport box. We arrange the transport of cord blood from the hospital to our processing lab in Covina, CA.

Processing

Processing your baby's umbilical cord blood takes place in our state-of-the-art laboratory facility. We offer a choice of MaxCell™ or StandardCell™ processing. MaxCell™ processing removes plasma and recovers the highest number of stem cells. StandardCell™ removes both plasma and red blood cells.

MaxCell™ Processing
(Plasma Depletion)

  • Removes plasma and recovers the highest number of stem cells
  • StemCyte's™ proprietary method
  • Final bags contain a volume of 30-80 mL depending on the collection volume
  • Several research studies have shown that this processing method results in a higher recovery of TNC (Total Nucleated Cells). TNC is a measure of the number of nucleated cells, which include the stem cells.

StandardCell™ Processing
(Red Cell Reduction)

  • Removes plasma and the majority of red blood cells
  • Most common method of processing cord blood
  • Final bags contain a volume of approximately 25 mL

Each collected cord blood unit, regardless of whether it undergoes StandardCell™ or MaxCell™ processing, undergoes testing to ensure quality, sufficient cell count, and viability of the stem cells. Testing includes bacterial/fungal cultures, total nucleated cell (TNC) count, viability assay, and CD34+ cell testing. The maternal blood sample is tested for infectious disease markers including HIV, hepatitis B, hepatitis C, syphilis, cytomegalovirus, HTLV, West Nile virus, and Chagas disease.

Freezing and Storage

A special solution is used to protect the cord blood cells during freezing. Each bag is frozen by a “controlled rate” freezing process, then it is stored in its own cassette within a stainless steel liquid nitrogen tank. The storage tanks are kept locked and are monitored continuously to ensure that the temperature stays below -150° C.

The exact expiration date of the unit is unknown because the field of umbilical cord blood transplantation is still relatively new. However, studies have shown that cord blood cells in frozen storage for as long as 26 years have the ability to engraft in patients. Many transplant experts believe cord blood stem cells will remain viable indefinitely, if appropriate processing and storage conditions are used. StemCyte™ uses the same strict procedures for storing frozen cord blood in both its public and private banks. The high quality and engraftment success of cord blood processed and stored by StemCyte™ has been clearly demonstrated after transplant in numerous patients with life-threatening diseases.

References

© 2014 StemCyte™. All rights reserved. Orange County Web Design by iCreativeCanvas